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Computational Biology

Analyze, visualize, and model biological data and systems

MathWorks® computational biology products provide tools to perform various analysis workflows for bioinformatics and systems pharmacology applications.

With these tools, you can perform end-to-end bioinformatics analyses locally or in cluster environments. You can view and explore integrated next generation sequencing (NGS) data using an app, identify differentially expressed genes or features, and discover copy number variants from NGS data.

Using integrated apps or at the command line, create and analyze dynamic models for quantitative systems pharmacology (QSP), physiologically based pharmacokinetic (PBPK), and pharmacokinetic/pharmacodynamic (PK/PD) applications . For instance, you can run parallel simulations and parameter scans to assess target feasibility and characterize biological variability. You can also use local and global sensitivity analyses to identify key parameters and estimate model parameters with nonlinear regression and mixed-effects techniques. Then, share your work and models using autogenerated reports and deployed applications.

Topics

Next Generation Sequencing

Quantitative Systems Pharmacology

PBPK and PK/PD Modeling