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Hello

I would like to pulse an input species. I read in the forums that repeated assignments can be used for this, but I am not exactly sure how to implement this. This is the MATLAB code that resembles what I would like the input pattern to be:

t = 0:1/1e3:60;
d = [10:2:30]';
x = @rectpuls;
y = pulstran(t,d,x);
plot(t,y)
hold off
xlabel('Time (s)')
ylabel('Waveform')

Thanks for any help! Aaron

I created a problem in Cody that approximates e. To test the user's solution, I compare their solution to e. What I want to do instead is compare the user's solution to my reference solution. The question is how do I call the reference solution in the test suite?
This is currently my test suite.
sol=exp(1);
y_correct = playgame();
assessVariableEqual('y_correct',sol);
I created several problems recently in CODY. Some of them got removed automatically. I was curious as to why.
It is possible that the problems used latex in their description, so I am not sure if that was the reason they got rejected by the cody server.
I created some problems last night and created a group too. All those are now missing.
Also my ranking progress, activites, badges earned last night are missing too.
Hi all,
I hope everyone is doing well and keeping safe. I was wondering, are there any Cody challenges for Simulink these days?
I saw a post from 2015 (https://blogs.mathworks.com/simulink/2015/08/07/modeling-and-simulation-challenge-in-cody/) and it seems there was a Simulink or "Modeling and Simulation Challenge" problem group, but I couldn't find this group anymore. Perhaps I missing something?
Thank you beforehand.
Tungky

Hello, We would like to share one of our QSP models with non-modeler colleagues for them to play with. Is there a simple way to generate a standalone app from a SimBiology model, with sliders allowing the user to change various parameter values?

Thank you,

Abed

Happy New Year, everyone! We hope you enjoyed the Cody contest in 2020, learned new MATLAB skills, and made a friend or two. While the 2020 contest has concluded, the fun and learning never end.

Please take the 1-minute survey to talk about your experience (only 2 required questions). Our goal is to make future contests better and more appealing to you, so your feedback is critical to us.

Thank you in advance and hope to see you again in the 2021 contest.

Hello, Does the 'sbiofit' function have functionality implemented for likelihood=based handling of BLoQ censored data, similar to functionality in NONMEM and other softwares? If not, are there plans to implement this?

Thanks,

Abed

I see this solution on the Cody solutions list. Solution 1949216
I am puzzled as to how this could possibly be rated as correct (size 48)
(BTW - I am pretty sure I saw this, or similar, before.)
function ans = fileread(varargin)
' ';
a=1;
b=3;
a=1;
b=3;a=1;
b=3;a=1;
b=3;a=1;
b=3; end

Hello,

I recently downloaded the GlobalSensitivityAnalysisApp. I am trying to perform a GSA using a simbiology model. I try running the App, but I get the error "No Sobol Indices Available to Plot. Configure the Sobol section and click the Compute button." I'm not sure if there is a step I'm overlooking. I'm following the instructional video for this app on the Matlab website, and I'm not sure what Configure the Sobol section is referring to. Any guidance would be greatly appreciated.

We are excited to announce that Cody Contest 2020 starts today! Again, the rule is simple - solve any problem and rate its difficulty. If you have any question, please visit our FAQs page first. Want to know your ranking? Check out the contest leaderboard .

Happy problem-solving! We hope you are a winner.

Chen Lin
Chen Lin
Last activity on 23 Jan 2021

Below are some FAQs for the Cody contest 2020. If you have any additional questions, ask your questions by replying to this post. We will keep updating the FAQs.

Q1: If I rate a problem I solved before the contest, will I still get a raffle ticket?

A: Yes. You can rate any problem you have solved, whether it was before or during the contest period.

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A: All badges will be awarded after the contest ends.

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A: If you are a winner, we will contact you to get your name and mailing address. You can find the list of winners on the Cody contest page .

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A: If the problem description is unclear, the test suite is broken, or similar concerns arise, post your question(s) as a comment on the specific problem page. If you are having a hard time solving a problem, you can post a comment to your solution attempt (after submitting it). However, do not ask other people to solve problems for you.

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A: Use Web Site Feedback . Select "MATLAB Central" from the category list.

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A: To rate a problem, you must solve that problem first and have at least 50 total points.

It's pretty odd how a solution that uses more characters than usual can be the "leading solution" of a Cody problem and have the least size. Compare these two codes that find the sum of integers from 1 to 2^x, which one uses fewer characters, thus should be the better solution?
function y = sum_int(x)
regexp '' '(?@y=sum(1:2^x);)'
end
function ans = sum_int(x)
sum(1:2^x)
end

How can I add the value of the error for each estimated parameter?

Hi, all

Recently I read the book "Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations: Principles, Methods, and Applications in the Pharmaceutical Industry" and find this state,"Since the unbound concentrations in plasma and blood are expected to be the same, fub , fup , and R are related as follows: R=Cb/Cp=(Cub·fup)/(Cup·fub) and R=fup/fub". I don't know whether it is reasonable to generally assume unbound concentrations in plasma and blood to be the same since components in whole blood and plasma are not the same. Is it common to see this equality in real situation?

Thanks for comment.

Hello,

We're working with a vendor to expand one of our current models that's written in SimBiology, but that vendor doesn't have a license to SimBiology. It would be nice if there existed a "Simbiology Viewer" which can be downloaded as a free Matlab package, and which would allow one to view but not edit SimBiology models. Are there any plans for something like this in the future? Something like this would make it much easier to share our models with people who don't have a license to SimBiology.

On a similar note, does anyone have any advice on the best ways to share SimBiology models currently? I noticed there's some functionality to export the tables of reactions, parameters, species, etc., and there's also some functionality to export the model into SBML.

Thank you,

Abed

If a large number of fair N-sided dice are rolled, the average of the simulated rolls is likely to be close to the mean of 1,2,...N i.e. the expected value of one die. For example, the expected value of a 6-sided die is 3.5.
Given N, simulate 1e8 N-sided dice rolls by creating a vector of 1e8 uniformly distributed random integers. Return the difference between the mean of this vector and the mean of integers from 1 to N.
function dice_diff = loln(N)
A=randi([1,N],1e8,1)
M=mean(A)
B=1:N
m=mean(B)
dice_diff =abs(M-m);
end
Here is my code, but it can't work out as it needs too long time to creat A.

Hi, all friends,

I want to record the fraction of drug absorbed in each intestinal segment, so I define a set of parameters with rate rule like: AbFraction_Colon= ((PeffColon*2/organismRadiusColon+paracellularAbsorption*organismFluxMucosaSerosa/Colon)*Colon.DrugDissolved)*Colon/InitialDose The attached figure shows the simulation result that overall PK profile (purple) seems OK, but I don't know why the absorption fraction line (red) starts from value of 1. Does anyone know the cause?

By the way, I am using model modified from "generic PBPK model"

Thanks for comment.

Hi, all friends

I am dealing with a confusing NCA result. As this result shows, AUC_infinity=0.8537 (μg*h/mL), DM=1 (mg). CL should be equal to DM/AUC_infinity but why is the calculated result 2.4491? There is no dimension along with value so I do not know if I ignore anything.

Does any one can handle with this situation? Thanks very much. I also post my used data (i.v.).

Hi, all friends

If I define a parameter, like solubility with dimension of milligram/milliliter and I want to refer it in an reaction equation in dimension of millimole/liter, suppose I have define its molecularweight, could I input this parameter directly in equation with specified dimension?