How to run Hotelling's t-square test in matlab?

I have two groups of subjects ('ACL-reconstructed' and 'Normal') and I would like to compare data from both limbs of each subject for both groups simultaneously. i.e. the ACL-reconstructed group contributes a 'reconstructed limb' and a 'contralateral limb' and the normal group also contributes a 'reconstructed limb' and a 'contralateral limb'. I was advised to conduct a Hotelling's t-square test for this analysis, but I am having trouble performing it.

Answer 1

[Star Strider]

If you want to do a pca first, you can do a Hotelling's T-squared statistic using it.

Otherwise, you first have to do an analysis of variance. See the documentation for Multivariate Analysis of Variance for Repeated Measures. There are a number of links to follow to allow you to write the code to analyse your data. It’s been years since I’ve done one of these, so I likely cannot help you further with the functions.

The ‘ACL reconstructed’ group have my sympathies!