Solutions

Scientists and engineers worldwide are battling the COVID-19 pandemic. Here are some examples of their work, including epidemiological analysis, diagnostics, and ventilator models.

COVID-19 Research and Development with MATLAB and Simulink

 

Characterization of the Second Wave of COVID-19 in India

Rajesh Ranjan et al, medRxiv, May 2 2021
paper preprint

ANFIS-Net for automatic detection of COVID-19

Afnan Al-ali et al, Nature: Scientific Reports, August 27 2021
paper

Machine learning detects SARS-CoV-2 and variants rapidly on DNA aptamer metasurfaces

Hulya Torun et al, medRxiv, August 8 2021
paper preprint

Smartphone science: apps test and track infectious diseases

Sandeep Ravindran, Nature, May 10 2021
paper

Analytical and qualitative investigation of COVID-19 mathematical model under fractional differential operator

Kamal Shah et al, Mathematical Methods in the Applied Sciences, August 22 2021
paper

A model and predictions for COVID-19 considering population behavior and vaccination

Thomas Usherwood et al, Nature: Scientific Reports, June 8 2021
paper

Genome Scale-Differential Flux Analysis reveals deregulation of lung cell metabolism on SARS-CoV-2 infection

Piyush Nanda and Amit Ghosh, PLOS Computational Biology, April 9 2021
paper

A novel methodology for epidemic risk assessment of COVID-19 outbreak

A. Pluchino et al, Nature: Scientific Reports, March 5 2021
paper

Toolbox to simulate and mitigate COVID-19 propagation

Zahrate El Oula Frihi et al, SoftwareX, June 2021
paper and GitHub MATLAB code repo

Mathematical model of COVID-19 intervention scenarios for São Paulo—Brazil

Osmar Pinto Neto et al, Nature Communications, January 18 2021
paper and Zenodo code

MSC-NTF (NurOwn®) exosomes: a novel therapeutic modality in the mouse LPS-induced ARDS model

Haggai Kaspi et al, Stem Cell Research & Therapy, January 19 2021
paper

Forecasting of medical equipment demand and outbreak spreading based on deep long short‑term memory network: the COVID‑19 pandemic in Turkey

Erdinç Koç  and Muammer Türkoğlu, Signal, Image and Video Processing, September 8 2020
paper

In-host Mathematical Modelling of COVID-19 in Humans

Esteban A. Hernandez-Vargas and Jorge X. Velasco-Hernandez, Annual Reviews in Control, September 30 2020
paper

Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19

Shidan Tosif et al, Nature Communications, November 11 2020
paper

Testing sewage to home in on Covid-19

Scott Murray, Institute for Data, Systems, and Society, October 28, 2020
article, paper with MATLAB code

Second Version of a COVID-19 Simulator

Cleve Moler, Cleve's Corner, March 29, 2020
blog post and MATLAB code and app

Temporal Dynamics of COVID-19 Outbreak and Future Projections: A Data-Driven Approach

Rajesh Ranjan, Transactions of the Indian National Academy of Engineering, June 6 2020
paper

Furin and the adaptive mutation of SARS-COV2: a computational framework

Ayesha Sohail et al, Modeling Earth Systems and Environment, August 26 2021
paper

Face masks effectively limit the probability of SARS-CoV-2 transmission

Yafang Cheng et al, Science, May 20 2021
paper, MATLAB code and data

Cognitive impairment and altered cerebral glucose metabolism in the subacute stage of COVID-19

Jonas A Hosp et al, BRAIN: A Journal of Neurology, April 3 2021
paper

COVID-19 intervention models: An initial aggressive treatment strategy for controlling the infection

Bismark Oduro and Vusi Mpendulo Magagula, Infect Dis Model, January 23 2021
paper

Controlling COVID-19 Outbreaks with Financial Incentives

Chaeyoung Lee et al, International Journal of Environmental Research and Public Health, January 15 2021
paper

The optimal lockdown intensity for COVID-19

Jonathan P. Caulkins et al, Journal of Mathematical Economics, February 3 2021
paper

A novel Covid-19 and pneumonia classification method based on F-transform

Turker Tuncer et al, Chemometrics and Intelligent Laboratory Systems, March 15 2021
paper

Electricity demand during pandemic times: The case of the COVID-19 in Spain

I. Santiago et al, Energy Policy, January 2021
paper

Optimal COVID-19 quarantine and testing strategies

Chad R. Wells et al, Nature Communications, 2021
paper

Management strategies in a SEIR-type model of COVID 19 community spread

Anca Rǎdulescu et al, Nature: Scientific Reports, December 4 2020
paper

Avoiding COVID-19: Aerosol Guidelines

Matthew Evans, medRxiv, June 5 2020
paper preprint

Mathematical analysis on the dynamics of COVID-19 in India using SIR Epidemic Model

Zargar and Khanday, Mapana Journal of Sciences, August 6 2020
paper

CORA: Toolbox for Reachability Analysis

Matthias Althoff, MATLAB File Exchange, August 4 2021
MATLAB Code

Data-driven estimation of COVID-19 community prevalence through wastewater-based epidemiology

Xuan Li et al, Science of the Total Environment, October 2021
paper

Compartmental Model Suggests Importance of Innate Immune Response to COVID‑19 Infection in Rhesus Macaques

Ericka Mochan et al, Bulletin of Mathematical Biology, May 26 2021
paper

Modeling the cardiac response to hemodynamic changes associated with COVID-19: a computational study

Luca Dede et al, Mathematical Biosciences and Engineering, April 15 2021
paper

A single dose of recombinant VSV-ΔG-spike vaccine provides protection against SARS-CoV-2 challenge

Yfat Yahalom-Ronen et al, Nature Communications,
December 16 2020
paper

Infection, inflammation and intervention: mechanistic modelling of epithelial cells in COVID-19

Nabil T. Fadai et al, Journal of the Royal Society Interface, February 17 2021
paper

Seismic evidence of the COVID-19 lockdown measures: a case study from eastern Sicily (Italy)

Andrea Cannata et al, EGU: Solid Earth, February 2 2021
paper

Principal Component Analysis Applications in COVID-19 Genome Sequence Studies

Bo Wang and Lin Jiang, Cognitive Computation, January 13 2021
paper

Comparative cost-effectiveness of SARS-CoV-2 testing strategies in the USA: a modelling study

Zhanwei Du et al, The Lancet: Public Health, February 4 2021
paper

Tracking COVID-19 using online search

Vasileios Lampos et al, NPJ Digital Medicine, February 8 2021
paper

The effect of weather data on the spread of COVID-19 in Jordan

Eman Abdelhafez et al, Environmental Science and Pollution Research, January 9 2021
paper

Design of 3D-printable nasopharyngeal swabs in MATLAB for COVID-19 testing

Yilun Sun et al, Transactions on Additive Manufacturing Meets Medicine, September 9 2020
paper

A quantitative and qualitative analysis of the COVID-19 pandemic model

Sarbaz Khoshnaw et al, Chaos, Solitons & Fractals, September 2020
paper

A COVID-19 Epidemiological Model for Community and Policy Maker Use

Alex De Visscher, Concordia University, arXiv, March 19, 2020
paper preprint with model code

The math behind epidemics

Alison Hill, Physics Today, November 1 2020
paper, MATLAB code

COVID-19 Spread Predictor

Ahmed Abel-Gawad, MATLAB File Exchange, July 18th
MATLAB code

COVID-19 SimBiology SEIR Model Examples

Fulden Buyukozturk, MATLAB File Exchange, May 29 2020

How to determine when COVID-19 pool testing will be most effective

Behind the Headlines, mathworks.com, August 6 2020
blog post

Ventilator Research and Development Resources

These MATLAB and Simulink examples and research papers were used to help with the ventilator shortage. Some are foundational references.

Pressure - Volume Controlled Mechanical Ventilator: Modeling and Simulation

Fikret YALÇINKAY, 9th International Conference on Electrical and Electronics Engineering (ELECO), 2015
paper

Ventilator Example with Closed-Loop Control on Low Cost Hardware

Steve Miller, GitHub, April 2020
GitHub repo with Simulink and Simscape models

Neonatal Ventilator Modeling using Simulink

Ravali K, GitHub, April 2020
GitHub repo with Simulink and Simscape models

Artificial Ventilation Simulator

Jakub R'afl, Czech Technical University in Prague, 2008
Masters thesis

A Novel Methodology for the Design of a Portable Ventilator

Subha Hency Jose P. et al, International Journal of Innovative Technology and Exploring Engineering (IJITEE), November 2019
paper

Medical Ventilator with Lung Model (Simscape Example)

Positive-pressure medical ventilator system that models the lung using Translational Mechanical Converter (MA), which converts moist air pressure into translational motion. 
Simscape model

Modelling and Simulation of Pressure Controlled Mechanical Ventilation System

Noman Q. Al-Naggar, Journal of Biomedical Science and Engineering (JBiSE), 2015
paper