Translating from MATLAB to Simulink

I have already written a MATLAB function and script to solve a large system of differential and alegraic equations. The original model uses ode15s to solve the stiff system of algebraic and differential equations. The equations also have several constants that are brought in to MATLAB from an Excel spreadsheet. I am now wanting to somehow incorporate this into Simulink so that I can do some parameter estimation/calibration. I have zero experience with Simulink. Is this the best method for performing parameter estimation? How do I go about "translating" my model as it currenlty exists to be run in Simulink for this purpose?

[Torsten]

If you have modelled your process in MATLAB by the system of differential and algebraic equations and you want to estimate parameters of this model against measurement data, you don't need Simulink. You can use MATLAB optimization functions, e.g. lsqcurvefit, for this.

Or do you want to extend your model by some physical blocks available in Simulink ?

[Matthew]

I am a little lost on how to use lsqcurvefit.

I have a model that has many (> 100) parameters. I only am concerned with calibrating a select few of those parameters to make the model results match the experimental results. The experimental results are just summary, mean datapoints of some critical measurements. How do I go about using lsqcurvefit for something like this? I only had gone the Simulink route because every time I search about parameter estimation in MATLAB, the resources always point to Simulink.

[Walter Roberson]

@Matthew

Do I understand correctly that you have a nonllnear model that has over 100 parameters, and each of them are unknown? Or are most of the parameters fixed in value and only a few are unknown?

Because if most of them are unknown, it is quite likely tthat lsqcurvefit will find misleading solutions. It is most common for nonlinear models to be quite sensitive to initial conditions.

For example something a simple as the sum of two phased guassians takes a lot of hunting around and frequently returns incorrect answers.

[Matthew]

The majority are either well known or do not impart much sensitivity to the model outcomes. I am only needing to estimate/calibrate no more than 10 of the parameters.